|
KMID : 0191120190340060048
|
|
Journal of Korean Medical Science
2019 Volume.34 No. 6 p.48 ~ p.48
|
|
|
Metabolic Syndrome Severity Score in Korean Adults: Analysis of the 2010?2015 Korea National Health and Nutrition Examination Survey
|
|
Huh Ji-Hye
Lee Jun-Hyeok
Moon Jin-Sil
Sung Ki-Chul
Kim Jang-Young
Kang Dae-Ryong
|
|
|
Abstract
|
|
|
Background: Continuous metabolic syndrome (MS) severity scores that can track metabolic risk in individuals over time have been developed for Western populations. The present study aimed to develop gender- and age-specific equations for MS severity scores in Korean adults.
Methods: Using data from the Korea National Health and Nutrition Examination Surveys (KNHANES) IV (2010?2012) and VI (2013?2015), we performed a confirmatory factor analysis of single MS factor that allowed for differential loadings across groups to generate gender- and age-specific, continuous MS severity scores. Then, we validated this equation in a different dataset of Korean adults.
Results: In confirmatory analysis, waist circumference had the highest factor loading, indicating that waist circumference had the strongest correlation with MS among Korean adults. Lower factor loadings (< 0.4) among Korean adults aged 40?59 years were noted for systolic blood pressure and fasting glucose. MS severity score values were significantly correlated with metabolic parameters, including high-sensitivity C-reactive-protein, glycated hemoglobin, and homeostasis model assessment of insulin resistance. Furthermore, MS severity scores well predicted traditional MS according to receiver operating characteristic analysis in a validation dataset (KNHANES VII). In a longitudinal cohort dataset, participants diagnosed with Adult Treatment Program III (ATP-III) MS after an initial assessment had progressively higher baseline MS severity scores in relationship to their time until ATP-III MS diagnosis.
Conclusion: The new MS severity score equations for Korean adults proposed in this study provide a clinically-accessible continuous measure of MS for potential use in identifying adults at higher risk for MS-related diseases and following changes within individuals over time.
|
|
|
KEYWORD
|
|
|
Metabolic Syndrome, Epidemiology, Obesity, Insulin Resistance
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|